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Gynecomastia Pills Reviews & Frequently Asked Questions

Gynecomastia Pills Reviews & Frequently Asked Questions2018-12-14T14:24:26+00:00

Gynecomastia pills are becoming one of the most sold speciality supplement pills in the market for men. For manufacturers who develop gynecomastia pills with other supplements, they account for about 5% of their overall sales. This is mainly fuelled by the rise of gynecomastia in men in North America and men in general throughout the world [1]. According to available statistics for the United States, 1 out of 3 young men and 1 out of 2 olden men has gynecomastia in one of the four grades [2]. The latest census reports that there are about 50 million men in the United States between the ages of 10-70 [3,4]. We are looking at about 17 million young adult men with gynecomastia in the United States alone.

statistics about gynecomastia

Gynecomastia in older men has long been discovered and accepted as somewhat normal by medical science. There is wider consensus in the medical community that every passing decade after 40 will result in a loss of natural testosterone and in older men, testosterone levels go down significantly as they go past the age of 65 [5]. Nevertheless some studies have shown that it is not true [6]. However, gynecomastia in young men is not natural. Breast tissue growth has serious and far reaching consequences in the social life and emotional health of young men. Before we go into details about gynecomastia pills, let’s take a look into the main types of breast enlargement in men. We will look at them in detail below.

an image of ideal users for gynecomastia pills


Gynecomastia is a medical term for excessive growth of breast tissue in adult men. This is the clinical, by-the-book definition of gynecomastia. Some breast tissue growth is natural for boys when they go through puberty but that should go away once they enter adulthood. Breast tissue growth during puberty is called pubertal gynecomastia and is a natural scenario [7]. However, if you have breast tissue growth as an adult above 21 years of age, that is something you need to be concerned.

anatomical illustration of gynecomastia

Pseudogynecomastia Or Lipomastia Or Adipomastia

Pseudogynecomastia is a common term used when breast enlargement is actually caused by pectoral fat being retained and deposited under and around the areola (nipples) [8]. This looks more or less the same as breast enlargement caused by excessive breast tissue growth or gynecomastia and that is exactly why it is called pseudo (fake) gynecomastia. The medical terms for pseudogynecomastia are lipomastia (lipo means fat lipids) and adipomastia (adipo means fat).

pseudogynecomastia anatomical illustration

Gynecomastia Diagnosis

Before using any gynecomastia pills, the first step you need to do is to actually make sure you have gynecomastia. You should never self-diagnose gynecomastia. Your family doctor or a general physician can diagnose gynecomastia but I highly recommend you see a doctor specializing in gynecomastia surgery. This is because a gynecomastia surgeon will be very experienced and adept with the physical examination procedure for diagnosing gynecomastia.

gynecomastia diagnosis

You will lie flat on your back with his hands clasped beneath your head. Using the separated thumb and forefinger, the doctor will slowly bring his fingers together from either side of the breast. If you have true gynecomastia, a rubbery or firm mound of tissue that is concentric with the nipple–areolar complex will be felt. If you have pectoral or chest fat, no such disk or tissue is found [9].

Difference In Physical Examination Findings

Gynecomastia Pseudogynecomastia Or Lipomastia
A mass under the nipple area of the breast with or without pain when touched or squeezed. Breast enlargement involves the both breasts equally and evenly, without pain during palpation. [9]

Theory Meets Reality

The strict classification of breast development into that which is caused by breast tissue and pectoral fat is for the sake of clarity. In reality, almost all cases of breast enlargement in men are caused by a mix of breast tissue and chest fat. This is called mixed gynecomastia [10]. I will explain this further when we talk about causes of gynecomastia and pseudogynecomastia.

anatomical illustration of mixed-gynecomastia

How Does Gynecomastia Occur

an image with the chemical structure of estrogen that causes gynecomastia in men

Even though you came to read about gynecomastia pills, let’s first understand what happens behind the scenes. Gynecomastia occurs as a result of excessive breast tissue, right ?. Yes that is the simple answer but how does this breast tissue occur is a bit complex. There are a number of factors that are involved in what leads up to breast tissue growth and they are 1) high estrogen 2) pectoral fat and 3) low testosterone [7]. These three form a negative feedback cycle that results in breast tissue growth or gynecomastia.

low testosterone causes gynecomastia in men

Negative Feedback Loop

Some men develop excess estrogen due to a number of reasons that includes a medical condition, use of medication, drug abuse or carry forward excess estrogen from their puberty and any number or multiple reasons lead to breast tissue growth [7]. Once your body starts to have more estrogen, the level of testosterone goes down and this is the first chain reaction in the negative feedback loop. Once your body is in a situation where it has a higher proportion of estrogen and less testosterone, it starts to hold and store more body fat in the chest as well in the abdomen and lowers its rate of metabolism and this forms the second stage of the negative feedback loop [11]. It has been scientifically proven that pectoral and abdominal fat levels are always associated with high estrogen levels in males [12]. Pectoral fat contains an enzyme called aromatase and acts as a secondary gland converting testosterone to estrogen [13]. It also binds itself to the breast tissue producing more estrogen and as a result more breast tissue. This forms the final stage of negative feedback loop.

the negative feedback loop that causes gynecomastia

So if we look at the root cause or pathophysiology of gynecomastia, it is high estrogen levels, low testosterone levels and pectoral fat as a secondary gland that produces estrogen forming a negative feedback loop feeding each other and causing excessive growth of breast tissue or gynecomastia [7]. The role of excess estrogen causing breast tissue growth was known for quite sometime but it was only recently that the role of fat and the negative feedback loop it create came to light. This has helped in the development, dosage and raising the effectiveness of gynecomastia pills.

Gynecomastia Pills : A Brief History

prescription gynecomastia pills includes serms's and AI's

Drugs to get rid of or limit the growth of breast tissue were first developed in the 70’s to fight breast cancer in women. There are two classes of drugs that have the potential to stop breast tissue and they are SERM’s (selective estrogen receptor modulators) [15,16] and AI (aromatize inhibitors) [14] SERM’s prevent the negative effects of excess estrogen and AI’s prevent the formation of estrogen in the first place. As far as gynecomastia is concerned, these are the chemical drugs that have the possibility to be used as gynecomastia pills.


Common Brand Name SERM’s

  • Nolvadex

  • Clomid

  • Fareston

Common Brand Name AI’s

  • Femara

  • Arimidex

  • Aromasin

The problem with using them is that SERM’s (Selective Estrogen Receptor Modulator) and AI’s (Aromatise Inhibitor) are two class of very strong drugs that has a number of side-effects. Both SERM’s & AI’s are prescription drugs used for treating breast cancer in women [17]. There are some rogue laboratories that sells these online. They are neither safe, reliable and are contaminated from being manufactured in fly-by-night make shift laboratories that are no different than an illicit meth labs .

serms and ai if used as gynecomastia pills require a prescription

SERM’s And AI’s Pros

  • AI’s prevent production of estrogen

  • SERM’s interrupts the effects of estrogen.

SERM’s And AI’s Side Effects

  • Prescribed as a last resort for breast cancer in women

  • Joint pain

  • Bone density loss (Osteoporosis)

  • Pain or pressure in the pelvis

  • Leg swelling or tenderness

  • Chest pain

  • Shortness of breath

  • Sudden vision problems

  • Severe headache

You might wonder why these drugs with such a long list of side effects are prescribed in the first place. You have to take into consideration the fact that they are prescribed for a life threatening medical condition like breast cancer. In that case the side effects are justified when compared against loss of life.

How To Get Rid Of Gynecomastia Without Surgery

If you want to get rid of gynecomastia without surgery, the key strategy is to break the negative feedback cycle of high estrogen levels >> low testosterone levels >> pectoral fat working as a secondary gland that produces even more estrogen. Natural gynecomastia pills contain one group of ingredients that have similar effects of chemical drugs that can stop and reverse the effects of estrogen. Another group of ingredients burn off chest fat so that it does not act as a breeding gland for estrogen production. One of the ingredients also signals the glands to produce more testosterone. This is the basic mechanism of action of gynecomastia pills that are available in the market. They help your body to break the negative feedback loop.

mechanism of action of gynecomastia pills

Natural Gynecomastia Pills

The gynecomastia pills & supplement industry is worth anywhere between $200-300 million per year and there have been a number of products that came and went in the last 10 years. Gynexin and Gynectrol are the only products that are manufactured in the United States.

natural gynecomastia pills

Natural gynecomastia pills are the safest non-surgical option that is currently available to get rid of gynecomastia. The goal of these supplements is to disrupt and reverse the negative feedback loop of high estrogen >> pectoral fat >> low testosterone with natural ingredients that have similar characteristics of SERM’s and AI’s. The main mechanism of action with these gynecomastia pills are to stop the production of excess estrogen, reverse the breast tissue growth, increase natural testosterone production and to burn off chest fat that acts as a secondary gland producing estrogen. So they are dosed for both addressing breast tissue growth as well as breaking and burning off pectoral fat. The two main products in the market are Gynexin and Gynectrol.

natural gynecomastia pills mechanism of action

Natural Ingredients Equivalent Of SERM’s & AI

Sclareolide is a natural testosterone producer used in gynecomastia pillsSclareolide is natural product derived from various plants Salvia sclarea, Salvia yosgadensis, Salvia haematodes, Salvia plebeia, Salvia miltiorrhiza, Salvia officinalis. These herbs commonly found in the Mediterranean, North Africa and Central Asian regions. Salvia haematodes roots increase sexual behaviuor of male rats [18]. Salvia plebeia suppresses the expressions of genes related to adipogenesis and lipogenesis activity [19]. Salvia officinalis improves insulin sensitivity, inhibits lipogenesis in adipocytes and reduces inflammation as judged by plasma cytokines [20, 21].

sclareolides and guggulsterones are natural serms and ai's

guggulsterone is a natural ingredient in gynecomastia pillsGuggulsterone is an Indian herbal ingredient and is processed from the gum of the Commiphora mukul tree. It signals the thyroid gland to produce more triiodothyronine that increases function of the thyroid gland [22,23,24] which has a direct catabolic effect on pectoral adipose tissue (chest fat) [25]. Guggulsterone may stimulate the thyroid gland to burn more pectoral fat. Guggulsterone influence numerous steroid receptors [26].

Theobromine cacao is an ingredient that prevents water retention in gynecomastia pills

theobromine cacao chemical structureTheobromine Cacao posses anti-breast cancer compounds [27]. Theobromine Cacao has compounds, which influences in a positive way our moods and our state of alertness [28]. These effects are due to antiradical properties of cocoa phenolics [29], which increase the plasma level of antioxidants to prevent the oxidation of LDL-cholesterol [30]. These particular properties are related to the protective mechanism of cocoa phenolics in heart disease [30]. Other relevant properties include their ability to modulate the immune response [31,32,33,34,35] and their anti-inflammatory [36,37,38] and anticarcinogenic properties [39].


GynexinGynexin is one of the gynecomastia pills that is available without a prescription. It is a speciality product that is only made in small numbers and available through their official website Gynexin is also the first custom developed Gynecomastia pill to manage gynecomastia without surgery.

No Ingredient What It Does
1 Sclareolides May suppress adipogenesis and lipogenesis activity, improve sexual function
2 Guggulsterone May increase the function of thyroid gland, which may increase lipolysis (Burns off chest fat)
3 Theobromine Cacao May modulate the immune response and has anti-inflammatory and anticarcinogenic properties
4 Caffeine Enhances focus and provides energy [40]
5 Chromium Reduce insulin resistance and to help reduce the risk of cardiovascular disease and type 2 diabetes [41]
6 Green Tea Extract works against high-fat diet-induced obesity and type II diabetes and could reduce the risk of coronary disease [42]
7 Titanium Dioxide Has antimicrobial effect [43]
8 Gelatin Capsule cover
9 Red Dye #40 AFC (Artificial Food Colour)
10 Red Dye #3 AFC (Artificial Food Colour)
11 Blue Dye #1 AFC (Artificial Food Colour)


  • 100% Natural Ingredients

  • Sclareolides & Guggulsterones

  • 8 Years In Market

  • First Ever Product For Breast Reduction


  • Is a nutrient and not a therapeutic agent and therefore will only be of benefit to those whose problems are due to suboptimal intake of ingredients.

  • No money back guarantee for opened bottles


Gynectrol chest fat burner supplementGynectrol is a supplement developed and marketed specifically for gynecomastia by Crazy Bulk, a very well known company in the fitness circle. The parent company specialises in developing supplements that are natural but has the potency of steroids and Gynectrol is their product that has natural ingredients with the potency of prescription drugs to get rid of gynecomastia. The official site is

No Ingredient What It Does
1 Sclareolides May suppress adipogenesis and lipogenesis activity, improve sexual function
2 Guggulsterone May increase the function of thyroid gland, which may increase lipolysis (Burns off chest fat)
3 Theobromine Cacao May modulate the immune response and has anti-inflammatory and anticarcinogenic properties
4 Caffeine Enhances focus and provides energy [40]
5 Chromium Reduce insulin resistance and to help reduce the risk of cardiovascular disease and type 2 diabetes [41]


  • 100% Natural Ingredients

  • Contains Sclareolides & Guggulsterones

  • Non-Proprietary Blend (Exact Dosage Known)

  • Made In U.S.A

  • Free Shipping

  • Coupon Codes


  • Is a nutrient and not a therapeutic agent and therefore will only be of benefit to those whose problems are due to suboptimal intake of ingredients.

  • No Money Back Guarantee For Opened Bottles

Both Gynexin and Gynectrol offers incentives if you are willing to share your results with them and these are some of the before-after pictures showing results after using one of these gynecomastia supplements. None of them have any stitches or scars and as such they cannot be from surgery.

Before & After Pictures

An image showing the chest size before and after using gynexin
An image showing the before and after picture of a man
An image of a man
An image that shows side by side the shape of a man
gynexin review before and after pictures
gynexin review before and after pictures


Gynexin review with before and after pictures
before and after images after using gynecomastia pills
before and after images following using gynecomastia pills
a man after losing gynecomastia and chest fat

Gynectrol VS Gynexin

I will review a few things like ingredients, price, shipping and money back guarantee in the table below. This will help you get a clear idea about how Gynexin and Gynectrol compares against each other.

comparison of leading gynecomastia pills Gynectrol and Gynexin
Product Gynectrol Gynexin
Mechanism Of Action Balances estrogen hormones & burn off chest fat Balances estrogen hormones & burn off chest fat
Ingredients Natural SERM’s & AI Natural SERM’s & AI
Main Ingredients Sclareolides, Guggulsterone & Theobromine Cacao Sclareolides, Guggulsterone & Theobromine Cacao
Proprietary Blend No – exact dosage information available Yes – exact dosage information not available
Free Shipping Yes Yes
Manufactured In United States United States
Money Back Guarantee Yes for unopened bottles Yes for unopened bottles
Price $61.99 for one month $69.95 for one month
Money Back Guarantee Yes for unopened bottles Yes for unopened bottles
Discount Codes Yes No
Manufacturer Reputation Reputed in fitness community for natural steroids Manufactures supplements for gynecomastia only
Official Website

Gynexin or Gynectrol ?

Both Gynexin and Gynectrol have been in the market for quite some time and have the same combination of ingredients. However, I recommend you get Gynectrol and these are my reasons for recommending Gynectrol. Gynectrol is a non-proprietary blend and what it means that, in a non-proprietary blend, you exactly know the dosage of the ingredients. Gynexin is a proprietary blend and you do not know how much of each ingredient is included. This is how Gynexin keeps their formula that they have been testing and tweaking for the last 8 years and there is nothing wrong with that from a commercial point of view.

recommended gynecomastia pill

I prefer recommending a product that I know the exact dosage of. Gynectrol is developed and manufactured by Crazy Bulk, a brand that is very popular among the fitness community and Gynectrol is used along with other cutting (losing body fat/weight) products and that is a very good sign of its reliability. Gynectrol is also cheaper by $8 per month and they also have discount codes almost all the time. Crazy Bulk is also a full-fledged supplement company with excellent customer service that is disrupting the fitness supplement industry with legal and natural ingredients. Based on my research and looking at before and after images submitted by users, I believe that Gynectrol users have achieved higher breast reduction than Gynexin users. Gynexin is also expensive costing $8 for one month’s supply and has the same ingredients as Gynectrol. Based on cost, available discount, reputation among users and customer service, I recommend Gynectrol.

recommended gynecomastia pill
gynectrol is one of the leading supplements to get rid of gynecomastia

Frequently Asked Questions About Gynecomastia Pills

We will go through some of the frequently asked questions about these gynecomastia pills. This is a compilation of questions that I have been asked over a period of 5 years since this site started. Feel free to contact me through the contact page if your question is not answered here.

frequently asked questions about gynecomastia pills

When Will I See Results ?

Sclareolides, Guggulsterone & Theobromine Cacao are natural ingredients that have similar characteristics of SERM’s (Selective Estrogen Receptor Modules) & AI’s (Aromatise Inhibitors). However, unlike their chemical counterparts, they require more time for their mechanism of action to start taking effect. You should start to see results by the end of the first month and most users see good results by the end of the second month.

How Many Bottles Should I Start With ?

I suggest you start with one bottle if you are concerned about the effectiveness of these gynecomastia pills. You can always order more by the end of the first month and it will arrive just in time. You will also be able to calculate the baseline response your body is returning in terms of chest reduction. Baseline response is the result that you achieve in a 30 day period. The first month’s baseline response can be used to calculate the time it will take for your desired level of chest reduction. You get discounts with multiple bottle purchases but again, I recommend to start with just one bottle.

Do I need To Control My Diet ?

One of the ways which these gynecomastia pills work is by burning off chest fat that 1) acts as a secondary gland producing estrogen and 2) give the feminine saggy look to your chest. They are also called supplements for a reason and it is that they are best used as supplementing a low-fat diet. The increased metabolism will burn more chest fat but if you also control fat intake, it will help you to achieve results faster. The key idea is to create a fat deficit where your body is not taking any more fat and it is burning chest fat at the same time. When you go on a high calorie/fat diet, it slows the results of these gynecomastia supplements. Fat is one key factor in the production of estrogen and by limiting fat intake in all ways possible, you are closing up the body’s opportunity to create estrogen and breast tissue.

Can I speed Up Breast Reduction ?

When using Gynexin or Gynectrol, there are a few things that you can do and they are optional. Even if you do not do the ingredients in them will work in their regular pace. Before that, let’s once again go through the process of breast reduction using one of the gynecomastia pills. The two main ingredients in Gynexin and Gynectrol are Sclareolides and Guggulsterones. Sclareolides suppress adipogenesis and lipogenesis activity, improve sexual function. The role of guggulsterones is to increase metabolism and facilitate lipolysis (breakdown and burning) of the pectoral fat and preventing it to act as a breeding ground for estrogen. Theobromine cacao modulates the immune response and has anti-inflammatory and anticarcinogenic properties. All the other ingredients acts as catalysts for increased metabolism. The mechanism of action of all these ingredients work to disrupt the negative feedback cycle of high estrogen levels >> low testosterone >> high pectoral fat creating more estrogen and causing gynecomastia.

the negative feedback loop that causes gynecomastia

One supplement that I recommend is TestoFuel, a testosterone booster specifically dosed for men to prevent gynecomastia. When you have a higher level of testosterone in your body, it first of all it suppresses the effects of excess estrogen and it also signals to body to develop wide, masculine chest structure. Higher testosterone levels also speeds up pectoral fat burning. TestoFuel is a prescription grade testosterone booster and is recommended by professional athletes like former Mr. Olympia Robby Robinson, who still uses it in his 70″s to be in peak shape. Again, this is optional and not mandatory for Gynexin or Gynectrol to work but if you can stack Gynectrol and TestoFuel together, it speeds up breast reduction.

Gynectrol is the most effective natural non-surgical option to get rid of gynecomastia. The ingredients in Gynectrol are dosed to balance the estrogen-testosterone levels and to burn off chest fat. If you think you will be happy with the reductions that you saw in the before and after images, I highly recommend you get Gynectrol.

  • Exclusively Developed For Gynecomastia

  • 100%  Natural With NO Side Effects

  • Manufactured In The United States

  • FREE Shipping

image of gynecomastia supplement bottle
Gynectrol Official Website

Medically Reviewed By

Medical reviewer at Gynecoma.comThe content of this page was fact checked and medically reviewed by Dr.Sergii Vasyliuk on October 22, 2018. You can read more about him and his credentials at our about page.